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Friday, August 7, 2020 | History

3 edition of Toxicity of arsenic and its compounds found in the catalog.

Toxicity of arsenic and its compounds

Paul G. Green

Toxicity of arsenic and its compounds

by Paul G. Green

  • 242 Want to read
  • 14 Currently reading

Published by Biomedical and Environmental Assessment Division, National Center for Analysis of Energy Systems, Department of Energy and Environment, Brookhaven National Laboratory, Associated Universities, Inc. in Upton, N.Y .
Written in English

    Subjects:
  • Arsenic -- Toxicology,
  • Arsenic compounds

  • Edition Notes

    StatementPaul G. Green.
    SeriesBNL-51510, BNL (Series) -- 51510.
    ContributionsNational Center for Analysis of Energy Systems. Biomedical and Environmental Assessment Division.
    The Physical Object
    Paginationiv, 29 p. :
    Number of Pages29
    ID Numbers
    Open LibraryOL17615034M
    OCLC/WorldCa53079717

    Skip to Main Content. Log in / Register. Log in / Register.   Arsenic, elem has a long and nefarious history; its very name has become synonymous with poison. In the 15th and 16th centuries, the Italian family of Borgias used arsenic as their favorite poison for political assassinations.

    Depending on the physical, chemical and biogeochemical processes and condition of the environment, various arsenic species can be present in water. Water soluble arsenic species existing in natural water are inorganic arsenic (iAs) and organic arsenic (oAs) species. All acidic species, according to the chemical equilibrium, have well-recognized molecular and ionic forms in : Ljubinka Rajakovic, Vladana Rajakovic-Ognjanovic.   Arsenic is commonly found in many foods both in its apparently nontoxic organic form and also in the more toxic inorganic form. Such arsenic has been reported in milk and dairy products, beef, pork, poultry, and cereal. Arsenic is also often found in rice, representing a potentially serious source of exposure in certain at-risk populations.

    However, due to its toxicity, there is concern about its presence in our diet. This book examines the real risks and impacts of arsenic in our lives. Looking at arsenic and its compounds, this book explores the presence of arsenic in food and water, the need to clarify its toxicity, and current scientific and public misconceptions about arsenic. Soluble forms of arsenic compounds are well absorbed orally. After absorption, most of the arsenic is bound to RBCs; it distributes to several tissues, with the highest levels found in liver, kidneys, heart, and lungs. In subchronic or chronic exposures, arsenic accumulates in skin, .


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Toxicity of arsenic and its compounds by Paul G. Green Download PDF EPUB FB2

View chapter Purchase book. Read full chapter. 3 Arsenic Toxicity. Arsenic compounds are known to be very toxic and carcinogenic. Chronic exposure to arsenic has more effects on health than any other toxicant, and the list continues to grow.

Arsenic poisoning takes between 8 and 14 years to manifest its effect on health. The publication then takes a look at the toxicity of arsenic and its compounds, as well as biological transformation of arsenic compounds in soil ecosystems and effects on plants; biotransformation of arsenic compounds and toxicity to freshwater and marine biota; and environmental transformation of arsenic in freshwater/marine ecosystems.

Arsenic poisoning is a medical condition that occurs due to elevated levels of arsenic in the body. If arsenic poisoning occurs over a brief period of time symptoms may include vomiting, abdominal pain, encephalopathy, and watery diarrhea that contains blood.

Long-term exposure can result in thickening of the skin, darker skin, abdominal pain, diarrhea, heart disease, numbness, and : Arsenic.

Arsenic and its compounds, especially the trioxide, are used in the production of pesticides, treated wood products, herbicides, and insecticides. These applications are declining due to the toxicity of arsenic and its compounds.

A few species of bacteria are able to use arsenic compounds as respiratory ciation: /ˈɑːrsnɪk/, (ARS-nik), as an adjective:. COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.

Arsenic and its compounds toxicity Arsenic is extremely poisonous for multicellular life, although several types of bacteria are capable of using arsenic compounds as respiratory metabolites. Pollution of groundwater with arsenic is a problem that affects millions of people around the : Margarita Stoytcheva, Roumen Zlatev.

Handbook of Arsenic Toxicology presents the latest findings on arsenic, its chemistry, its sources and its acute and chronic effects on the environment and human health.

The book takes readings systematically through the target organs, before detailing current preventative and counter measures. Arsenic and many of its compounds are especially potent poisons. Arsenic disrupts ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by competing with phosphate it uncouples oxidative phosphorylation, thus inhibiting energy-linked reduction of NAD+, mitochondrial respiration, and ATP synthesis.

ARSENIC-INDUCED NEPHROTOXICITY AND HEPATOTOXICITY. Arsenic concentrates in the kidney during its urinary elimination that affects the function of proximal convoluted tubules.[58,59] Arsenic-induced oxidative stress increases the expression of HO-1 and MAPK, which by regulating various transcription factors such as activator protein-1 (AP-1), activating transcription factor-2 (ATF-2), and.

Organoarsenic chemistry is the chemistry of compounds containing a chemical bond between arsenic and carbon.A few organoarsenic compounds, also called "organoarsenicals," are produced industrially with uses as insecticides, herbicides, and general these applications are declining in step with growing concerns about their impact on the environment and human health.

Arsenic Compounds ARSENIC COMPOUNDS (A) Hazard Summary Arsenic, a naturally occurring element, is found throughout the environment; for most people, food is the major source of exposure. Acute (short-term) high-level inhalation exposure to arsenic dust or fumes has.

The relative toxicity of an arsenical depends primarily on. inorganic or organic form, valence state, solubility, physical state and purity, and; rates of absorption and elimination [ATSDR ]. The toxicity of arsenic compounds can vary greatly. In general, arsenic compounds can be ranked from highest to lowest toxicity: inorganic trivalent.

Arsenic trioxide, sold under the brand name Trisenox among others, is an inorganic compound and medication. As an industrial chemical major uses include in the manufacture of wood preservatives, pesticides, and glass. As a medication it is used to treat a type of cancer known as acute promyelocytic leukemia.

For this use it is given by injection into a al formula: As, ₂O, ₃. The urinary output of arsenic compounds as total arsenic following the ingestion of arsenic trioxide amounted to 40% of the ingested amount during the first 12 hours, and 70% by 72 hours.

Arsenic is a naturally occurring allotropic pnictogen and metalloid trace element with atomic symbol As, atomic num and atomic weight that is found in water, air, food, and soil, and has a role as a micronutrient.

Arsenic, which is highly toxic with acute or chronic exposure to moderate or high levels through an unknown mechanism of action, is used in many industrial processes, as. Source, distribution, toxicity and remediation of arsenic in the environment containing arsenic also contributes to the emission of arsenic into the atmosphere [3] (see Figure 1(AB)).

Natural sources such as volcanoes can contribute to the release of arsenic into the atmosphere (Figure 1(AC)). Arsenic exerts its toxicity by inactivating up to enzymes, especially those involved in cellular energy pathways and DNA synthesis and repair. Acute arsenic poisoning is associated initially with nausea, vomiting, abdominal pain, and severe diarrhoea.

Encephalopathy and peripheral neuropathy are reported. Chronic arsenic toxicity results in Cited by: The second section, Relevant Chemical Considerations, provides a brief account of arsenic's chemistry that is relevant to considerations of toxicity and carcinogenicity.

In the third section, Analysis of Arsenic Compounds, general methods that have been used to analyze arsenic and its species are outlined. The results of applying these methods.

Arsenic can cause serious effects of the neurologic, respiratory, hematologic, cardiovascular, gastrointestinal, and other systems.

Arsenic is a carcinogen in multiple organ systems. Interindividual and population differences in arsenic methylation and nutritional status may be factors in susceptibility to arsenic toxicity. Arsenic has become a great concern because of its chronic and epidemic effects on human, plant and animal health (Hughes et al., ).

Presenting in the ter. Arsenic poisoning, or arsenicosis, happens when a person takes in dangerous levels of arsenic.

Arsenic is a natural semi-metallic chemical that is found all over the world in : Michael Paddock.Arsenic and arsenic compounds were considered by previous IARC Working Groups in, and (IARC, ). Since that time, new data have become available, these have been incorported in the Monograph, and taken into consideration in the present evaluation.Arsenic and its compounds 3 Arsine is a highly poisonous and flammable gas.

The following discussion of arsenic and its compounds is relevant to arsine. Any specific or additional considerations needed with arsine is discussed in the section following Size: 77KB.